Show simple item record

dc.contributor.authorDevkota, Govinda Prasad
dc.contributor.authorCarson, William P.
dc.contributor.authorHartley, C. Scott
dc.description.abstractControl over the folding of oligomers, be it broad induction of a preferred helical handedness or subtle changes in the orientations of individual functional groups, is important for applications ranging from molecular recognition to long-range conformational communication. Here, we report a series of ortho-phenylene hexamers functionalized with achiral and chiral amides at their termini. NMR spectroscopy, taking advantage of F-19 labeling, allows multiple conformers to be detected for each compound. In combination with CD spectroscopy and DFT calculations, specific geometries corresponding to each conformer have been identified and quantified. General conclusions about the effect of sterics and the amide linker on conformational behavior have been drawn, revealing some similarities and key differences with previously reported imines. A model for twist sense control has been developed that is supported by computational models.en_US
dc.rightsAttribution 3.0 United States*
dc.titleData archive for "Conformational control of ortho-phenylenes by terminal amides"en_US
dc.typeJournal Articleen_US

Files in this item


This item appears in the following Collection(s)

  • Hartley, Scott
    Dr. Scott Hartley - Professor, Chemistry & Biochemistry

Show simple item record

Attribution 3.0 United States
Except where otherwise noted, this item's license is described as Attribution 3.0 United States